Seza Ozen Selected Research

Familial Mediterranean Fever (Periodic Disease)

12/2022	Response to: 'Correspondence on 'Long-term efficacy and safety of canakinumab in patients with colchicine-resistant familial Mediterranean fever: results from the randomised phase III CLUSTER trial'' by Satis et al.
1/2022	The pyrin inflammasome aggravates inflammatory cell migration in patients with familial Mediterranean fever.
1/2022	Biologics for immunoglobulin A vasculitis: targeting vasculitis or comorbid disease?
9/2021	Inflammation-related differentially expressed common miRNAs in systemic autoinflammatory disorders patients can regulate the clinical course.
12/2020	Comment on: Successful hydroxychloroquine treatment for familial Mediterranean fever in a Japanese patient with concurrent systemic lupus erythematosus.
11/2020	Analysis of polymorphisms in the colchicine binding site of tubulin in colchicine-resistant familial Mediterranean fever patients.
10/2020	Long-term efficacy and safety of canakinumab in patients with colchicine-resistant familial Mediterranean fever: results from the randomised phase III CLUSTER trial.
1/2020	Colchicine and Leukopenia: Clinical Implications.
1/2020	Ancient familial Mediterranean fever mutations in human pyrin and resistance to Yersinia pestis.
12/2019	What's new in autoinflammation?

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Seza Ozen Research Topics

Disease

37	Familial Mediterranean Fever (Periodic Disease) 12/2022 - 05/2003
22	Inflammation (Inflammations) 01/2022 - 09/2003
19	Fever (Fevers) 01/2022 - 07/2003
17	Vasculitis (Vasculitides) 01/2022 - 11/2002
14	Amyloidosis 12/2019 - 04/2002
12	Juvenile Arthritis (Juvenile Idiopathic Arthritis) 08/2021 - 01/2010
10	Mevalonate Kinase Deficiency 01/2022 - 01/2006
10	Arthritis (Polyarthritis) 01/2022 - 07/2003
10	Purpura 01/2021 - 11/2002
9	Polyarteritis Nodosa (Periarteritis Nodosa) 01/2022 - 09/2005
8	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2022 - 09/2005
7	Mucocutaneous Lymph Node Syndrome (Kawasaki Disease) 01/2022 - 01/2018
6	Infections 02/2022 - 08/2009
6	Cryopyrin-Associated Periodic Syndromes 01/2022 - 01/2006
5	Rheumatic Diseases (Rheumatism) 01/2022 - 01/2017
5	Nephritis 12/2020 - 04/2002
5	Proteinuria 04/2016 - 08/2004
4	Takayasu Arteritis (Arteritis, Takayasu's) 11/2022 - 01/2007
4	Necrosis 01/2022 - 03/2010
4	Disease Progression 01/2022 - 11/2002
4	Macrophage Activation Syndrome 01/2020 - 12/2012
4	Glomerulonephritis 02/2007 - 07/2003
3	COVID-19 02/2022 - 11/2021
3	Lupus Nephritis 01/2022 - 01/2010
3	Bites and Stings (Sting) 01/2022 - 12/2019
3	Anaphylaxis (Anaphylactic Shock) 05/2020 - 12/2019
3	Serositis 01/2017 - 09/2005
3	Hypertension (High Blood Pressure) 09/2012 - 12/2005
3	Chronic Kidney Failure (Chronic Renal Failure) 12/2007 - 05/2002
2	chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature 01/2022 - 01/2022
2	Lymphopenia (Lymphocytopenia) 10/2021 - 01/2007
2	Uveitis 08/2021 - 04/2010
2	Exanthema (Rash) 08/2021 - 06/2017
2	IgA Vasculitis (Purpura, Schoenlein Henoch) 12/2020 - 02/2008
2	Behcet Syndrome (Behcet's Syndrome) 11/2020 - 09/2017
2	Hypersensitivity (Allergy) 05/2020 - 12/2019
2	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 01/2020 - 01/2018
2	Dermatomyositis (Dermatopolymyositis) 01/2020 - 01/2020
2	deficiency of adenosine deaminase 2 12/2019 - 09/2017
2	Pyogenic arthritis, pyoderma gangrenosum, and acne 01/2018 - 01/2006
2	Systemic Vasculitis 01/2018 - 08/2009
2	autosomal dominant familial Periodic fever 01/2018 - 01/2013
2	Rare Diseases (Rare Disease) 08/2017 - 04/2015
2	Hepatitis 12/2016 - 12/2016
2	Cardiovascular Diseases (Cardiovascular Disease) 11/2014 - 12/2007
2	Abdominal Pain (Pain, Abdominal) 05/2010 - 07/2003

Drug/Important Bio-Agent (IBA)

18	Colchicine FDA LinkGeneric 12/2022 - 04/2002
13	Immunoglobulin A (IgA)IBA 01/2022 - 04/2002
10	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 01/2020 - 11/2002
9	Acute-Phase Proteins (Acute-Phase Protein)IBA 01/2017 - 07/2003
8	SteroidsIBA 01/2022 - 01/2007
8	Biological ProductsIBA 01/2022 - 08/2009
8	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2021 - 07/2003
8	C-Reactive ProteinIBA 08/2021 - 06/2004
7	canakinumab FDA Link 12/2022 - 06/2012
7	PyrinIBA 01/2022 - 09/2003
7	Interleukin-1 (Interleukin 1)IBA 01/2022 - 02/2010
6	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022 - 01/2007
6	Proteins (Proteins, Gene)FDA Link 05/2021 - 01/2006
6	Serum Amyloid A Protein (Serum Amyloid A)IBA 06/2017 - 07/2003
5	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2022 - 02/2010
5	InterferonsIBA 01/2022 - 01/2018
5	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2021 - 01/2007
5	Biomarkers (Surrogate Marker)IBA 12/2020 - 01/2004
5	Amyloid (Amyloid Fibrils)IBA 04/2016 - 07/2003
4	Etanercept (Enbrel)FDA Link 01/2022 - 08/2009
4	Rituximab (Mabthera)FDA Link 01/2022 - 08/2009
4	AutoantibodiesIBA 01/2021 - 01/2006
4	CytokinesIBA 01/2018 - 09/2003
3	Intravenous Immunoglobulins (IVIG)FDA Link 01/2022 - 07/2007
3	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2022 - 01/2018
3	MicroRNAs (MicroRNA)IBA 12/2021 - 11/2020
3	Methotrexate (Mexate)FDA LinkGeneric 12/2021 - 01/2007
3	Pharmaceutical PreparationsIBA 08/2021 - 12/2019
3	DNA (Deoxyribonucleic Acid)IBA 11/2020 - 02/2008
3	tocilizumab (atlizumab)FDA Link 05/2020 - 12/2019
3	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 12/2019 - 07/2017
3	Azathioprine (Imuran)FDA LinkGeneric 04/2010 - 05/2007
2	InflammasomesIBA 01/2022 - 01/2020
2	Infliximab (Remicade)FDA Link 01/2022 - 08/2009
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2022 - 01/2022
2	Antirheumatic Agents (DMARD)IBA 01/2022 - 01/2022
2	Immunoglobulin E (IgE)IBA 10/2021 - 12/2019
2	Rheumatoid FactorIBA 08/2021 - 01/2011
2	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 12/2020 - 11/2017
2	AcidsIBA 12/2020 - 05/2003
2	Adenosine DeaminaseIBA 01/2020 - 03/2014
2	InterleukinsIBA 12/2019 - 08/2017
2	Anti-Bacterial Agents (Antibiotics)IBA 11/2019 - 05/2010
2	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2019 - 11/2009
2	VaccinesIBA 12/2016 - 12/2016
2	Hydrocortisone (Cortisol)FDA LinkGeneric 11/2010 - 03/2010
2	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 11/2009 - 05/2002
2	Mitochondrial DNA (mtDNA)IBA 11/2005 - 01/2005
2	Peroxidase (Myeloperoxidase)IBA 07/2003 - 11/2002
1	Interleukin-6 InhibitorsIBA 11/2022

Therapy/Procedure

21	Therapeutics 11/2019 - 01/2004
3	Kidney Transplantation 12/2007 - 04/2002
2	Biological Therapy 01/2022 - 08/2009
2	Injections 12/2019 - 08/2014